Markets were mostly higher on Wednesday.
The S&P 500 rose 0.2 percent and the STOXX Europe 600 rose 0.1 percent.
Markets were able to rise despite the continuing threat from COVID-19.
Europe is now once again the epicentre of the pandemic, with Slovakia, the Czech Republic, the Netherlands and Hungary all reporting new highs in daily infections on Wednesday.
The European Centre for Disease Prevention and Control has recommended vaccine boosters for all adults.
However, the World Health Organization's director-general Tedros Adhanom Ghebreyesus said on Wednesday: "We're concerned about the false sense of security that vaccines have ended the pandemic and people who are vaccinated do not need to take any other precautions."